丁酸梭菌
化学
抗氧化剂
微生物学
生物化学
梭菌
DNA
食品科学
生物
发酵
细菌
遗传学
作者
Guolin Cai,Yuting Geng,Yifan Liu,Shaojie Yang,Xiaomin Li,Haiyan Sun,Jian Lü
标识
DOI:10.1111/1750-3841.16609
摘要
Exopolysaccharides (EPSs) of probiotics are naturally nontoxic antioxidants with some interesting biological activities. This research aims to explore the structural and antioxidant properties of the EPS from Clostridium butyricum, a probiotics widely existed in human and animal intestines. EPS of C. butyricum RO-07 was purified through a combination of anion-exchange column chromatography and gel chromatography and determined to be composed of glucosamine, arabinose, galactosamine, galactose, glucose, and xylose in a molar ratio of 1:1:1:2:1:1 with a molecular weight 1.23 × 104 Da. It exhibited a stronger antioxidant activity than ascorbic acid, with scavenging activities up to 75.2% and 95.0% against hydroxyl radical (•OH) and superoxide radical (O2- •), respectively. It also performed protective effects on DNA against radiation destruction by ultraviolet and reactive oxygen species generated oxidation stress. With these superior advantages in oxidants and radiation resistance, the EPS from C. butyricum RO-07 therefore has great potential to be applied in food and cosmetic industry.
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