Radical Arylaminoformylation of Activated Alkenes to Amides Containing All‐Carbon Quaternary Stereocenters

Abstract Herein we report an Ag + /S 2 O 8 2− inducted measure for functionalized succinyl diamides bearing an all‐carbon quaternary stereocenter via a radical aminoformylation/aryl‐migration/desulfonylation cascade. The improved process is developed employing readily available and inexpensive oxalic monoamide as a carbamoyl radical precursor through radical Smiles rearrangement. Additionally, the tolerance to oxygen and water, operational simplicity, convenient reagents, as well as scalability, enhance the practical value of the proposed synthesis strategy.