Global, regional, and national lifetime risks of developing and dying from gastrointestinal cancers in 185 countries: a population-based systematic analysis of GLOBOCAN

医学 胃肠道癌 预期寿命 人口 癌症 入射(几何) 内科学 胰腺癌 结直肠癌 人口学 环境卫生 光学 物理 社会学
作者
Shaoming Wang,Rongshou Zheng,Jiayue Li,Hongmei Zeng,Li Li,Ru Chen,Kexin Sun,Bingfeng Han,Freddie Bray,Wenqiang Wei,Jie He
出处
期刊:The Lancet Gastroenterology & Hepatology [Elsevier]
卷期号:9 (3): 229-237 被引量:89
标识
DOI:10.1016/s2468-1253(23)00366-7
摘要

Background Gastrointestinal cancers account for a quarter of the global cancer incidence and a third of cancer-related deaths. We sought to estimate the lifetime risks of developing and dying from gastrointestinal cancers at the country, world region, and global levels in 2020. Methods For this population-based systematic analysis, we obtained estimates of gastrointestinal cancer incidence and mortality rates from GLOBOCAN for 185 countries, alongside all-cause mortality and population data from the UN. Countries were categorised into quartiles of the Human Development Index (HDI). The lifetime risk of gastrointestinal cancers was estimated with a standard method that adjusts for multiple primaries, taking into account competing risks of death from causes other than cancer and life expectancy. Findings The global lifetime risks of developing and dying from gastrointestinal cancers from birth to death was 8·20% (95% CI 8·18–8·21) and 6·17% (6·16–6·18) in 2020. For men, the risk of developing gastrointestinal cancers was 9·53% (95% CI 9·51–9·55) and of dying from them 7·23% (7·22–7·25); for women, the risk of developing gastrointestinal cancers was 6·84% (6·82–6·85) and of dying from them 5·09% (5·08–5·10). Colorectal cancer presented the highest risk, accounting for 38·5% of the total lifetime risk of developing, and 28·2% of dying from, gastrointestinal cancers, followed by cancers of the stomach, liver, oesophagus, pancreas, and gallbladder. Eastern Asia has the highest lifetime risks for cancers of the stomach, liver, oesophagus, and gallbladder, Australia and New Zealand for colorectal cancer, and Western Europe for pancreatic cancer. The lifetime risk of gastrointestinal cancers increased consistently with increasing level of HDI; however, high HDI countries (the third HDI quartile) had the highest death risk. Interpretation The global lifetime risk of gastrointestinal cancers translates to one in 12 people developing, and one in 16 people dying from, gastrointestinal cancers. The identified high risk and observed disparities across counties warrants context-specific targeted gastrointestinal cancer control and health systems planning. Funding Beijing Nova Program, CAMS Innovation Fund for Medical Sciences, and Talent Incentive Program of Cancer Hospital, CAMS (Hope Star).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
青羽落霞完成签到 ,获得积分10
刚刚
刚刚
qweasdzxcqwe完成签到,获得积分10
刚刚
1秒前
2秒前
2秒前
疯狂的乌冬面完成签到,获得积分10
3秒前
科研通AI2S应助复杂的熊猫采纳,获得10
3秒前
小库里2025完成签到 ,获得积分10
4秒前
li完成签到,获得积分10
4秒前
自然紫山完成签到,获得积分10
5秒前
5秒前
hmwu_test发布了新的文献求助10
6秒前
Shandongdaxiu发布了新的文献求助10
6秒前
刘城发布了新的文献求助10
6秒前
llzuo发布了新的文献求助10
7秒前
8秒前
8秒前
追寻紫安完成签到,获得积分10
9秒前
迷人的天抒应助qweasdzxcqwe采纳,获得10
9秒前
bkagyin应助qweasdzxcqwe采纳,获得10
10秒前
壮观复天完成签到 ,获得积分10
10秒前
10秒前
dalong完成签到,获得积分10
10秒前
开朗的踏歌完成签到,获得积分10
10秒前
10秒前
xxxxxx完成签到,获得积分10
10秒前
xiaoxiao发布了新的文献求助10
12秒前
一只蓉馍馍完成签到,获得积分10
13秒前
的地方法规完成签到,获得积分10
14秒前
14秒前
咖啡的腿毛完成签到 ,获得积分10
15秒前
快乐小白菜完成签到,获得积分10
15秒前
面包发布了新的文献求助10
15秒前
Allen完成签到,获得积分10
16秒前
TranYan完成签到,获得积分10
16秒前
涣醒完成签到,获得积分10
16秒前
zyz完成签到,获得积分10
16秒前
含蓄的孤丝完成签到,获得积分10
17秒前
da完成签到,获得积分10
17秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968637
求助须知:如何正确求助?哪些是违规求助? 3513552
关于积分的说明 11168493
捐赠科研通 3248935
什么是DOI,文献DOI怎么找? 1794554
邀请新用户注册赠送积分活动 875188
科研通“疑难数据库(出版商)”最低求助积分说明 804691