低钾血症
内分泌系统
医学
重症监护医学
临床实习
激素
生物信息学
内分泌学
生物
家庭医学
作者
Silas A Culver,Nawar Suleman,Varun Kavuru,Helmy M. Siragy
标识
DOI:10.1210/clinem/dgae201
摘要
Abstract The majority of disorders that cause renal potassium wasting present with abnormalities in adrenal hormone secretion. While these findings frequently lead patients to seek endocrine evaluation, clinicians often struggle to accurately diagnose these conditions, delaying treatment and adversely impacting patient care. At the same time, growing insight into the genetic and molecular basis of these disorders continues to improve their diagnosis and management. In this review, we outline a practical integrated approach to the evaluation of renal hypokalemia syndromes that are seen in endocrine practice while highlighting recent advances in understanding of the genetics and pathophysiology behind them.
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