类风湿性关节炎
医学
动物模型
疾病
自身免疫性疾病
关节炎
发病机制
病态的
免疫学
内科学
作者
Zihong Wei,Jeff Wang,Hiroto Kawashima
标识
DOI:10.1016/j.azn.2024.03.001
摘要
Rheumatoid arthritis (RA) is an autoimmune disease that causes significant disability and has a high recurrence rate. Currently, there is no cure for this disease. Identifying the cause of RA and developing new targeted therapeutic drugs have become priority research areas. Animal models of RA are critical in understanding the disease's pathogenesis and the effectiveness of drug treatments. This review summarizes the most recent progress in developing mouse models of autoimmune arthritis to serve as a reference for the study of experimental animal models that are more similar to the pathological features of human RA.
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