医学
甲状腺癌
接收机工作特性
比例危险模型
肿瘤科
内科学
甲状腺
长非编码RNA
生存分析
癌症
计算生物学
核糖核酸
基因
遗传学
生物
作者
Lujia Liu,Jianrong Xu,Xuying Sun,Haitao Zheng
出处
期刊:Biomarkers in Medicine
[Future Medicine]
日期:2023-08-01
卷期号:17 (15): 643-654
标识
DOI:10.2217/bmm-2023-0216
摘要
Aims: We aimed to investigate the value of cuproptosis-related lncRNA in screening out high-risk thyroid cancer patients. Materials & methods: RNA sequencing data of thyroid cancer were obtained from The Cancer Genome Atlas. A cuproptosis-related lncRNA signature was constructed by using Cox regression. Results: Four cuproptosis-related lncRNAs were used to construct a survival prognosis model for thyroid cancer. The receiver operating characteristic curve showed that the area under the curve reached 0.830 at 1 year, 0.790 at 3 years and 0.824 at 5 years. Conclusion: The model may help to screen out thyroid cancer patients at high risk, and thus develop more appropriate treatment strategies.
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