Coarse-to-fine prior-guided attention network for multi-structure segmentation on dental panoramic radiographs

Objective. Accurate segmentation of various anatomical structures from dental panoramic radiographs is essential for the diagnosis and treatment planning of various diseases in digital dentistry. In this paper, we propose a novel deep learning-based method for accurate and fully automatic segmentation of the maxillary sinus, mandibular condyle, mandibular nerve, alveolar bone and teeth on panoramic radiographs.Approach. A two-stage coarse-to-fine prior-guided segmentation framework is proposed to segment multiple structures on dental panoramic radiographs. In the coarse stage, a multi-label segmentation network is used to generate the coarse segmentation mask, and in the fine-tuning stage, a prior-guided attention network with an encoder-decoder architecture is proposed to precisely predict the mask of each anatomical structure. First, a prior-guided edge fusion module is incorporated into the network at the input of each convolution level of the encode path to generate edge-enhanced image feature maps. Second, a prior-guided spatial attention module is proposed to guide the network to extract relevant spatial features from foreground regions based on the combination of the prior information and the spatial attention mechanism. Finally, a prior-guided hybrid attention module is integrated at the bottleneck of the network to explore global context from both spatial and category perspectives.Main results. We evaluated the segmentation performance of our method on a testing dataset that contains 150 panoramic radiographs collected from real-world clinical scenarios. The segmentation results indicate that our proposed method achieves more accurate segmentation performance compared with state-of-the-art methods. The average Jaccard scores are 87.91%, 85.25%, 63.94%, 93.46% and 88.96% for the maxillary sinus, mandibular condyle, mandibular nerve, alveolar bone and teeth, respectively.Significance. The proposed method was able to accurately segment multiple structures on panoramic radiographs. This method has the potential to be part of the process of automatic pathology diagnosis from dental panoramic radiographs.