磷酸西他列汀
医学
内科学
糖尿病性心肌病
内分泌学
磷酸西他列汀
链脲佐菌素
糖尿病
二肽基肽酶-4抑制剂
SMAD公司
转化生长因子
心肌病
2型糖尿病
心力衰竭
作者
Anfal F. Bin Dayel,Asma S. Alonazi,Nawal M. Al‐Rasheed,Maha A. Al‐Amin,Wedad S. Sarawi,Abeer O. Alharbi,Nahla’a A Alabbad,Danah A. Albuaijan,Dareen Alassiri,Alanoud F Aljarbua,Fatimah K Almusaytir,Nouf M. Al‐Rasheed
摘要
Diabetic cardiomyopathy is a known complication of diabetes mellitus. Herein, we aimed to determine whether glycemic control mediated by sitagliptin, a dipeptidyl peptidase-4 inhibitor, can ameliorate diabetic myocardial abnormalities by modulating TGF-β signaling via the SMAD and integrin-linked kinase (ILK) pathways.
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