医学
食物过敏
重症监护医学
过敏
体格检查
口服食物挑战赛
免疫学
流行病学
免疫系统
免疫球蛋白E
不利影响
抗体
病理
内科学
出处
期刊:The Lancet
[Elsevier]
日期:2002-08-01
卷期号:360 (9334): 701-710
被引量:250
标识
DOI:10.1016/s0140-6736(02)09831-8
摘要
Food allergy encompasses a range of disorders that result from adverse immune responses to dietary antigens. This group of conditions includes acute, potentially fatal reactions, and a host of chronic diseases that mainly affect the skin and gastrointestinal tract. Tools for diagnosis and management have not changed much in the past two decades, and include the clinical history, physical examination, tests for specific IgE antibody to suspected foods, elimination diets, oral food challenges, and provision of medications such as epinephrine for emergency treatment. However, much research in the past few years has enhanced our understanding of the clinical, epidemiological, and immunological aspects of these disorders. In this review I will discuss these advances and incorporate them into an improved diagnostic and management scheme. Additionally, emergent diagnostic, treatment, and prevention strategies are reviewed.
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