骨质疏松症
双膦酸盐
医学
骨重建
骨吸收
唑来膦酸
内科学
骨矿物
骨密度保护剂
内分泌学
出处
期刊:Clinical calcium
日期:2009-01-01
卷期号:19 (1): 63-73
被引量:1
摘要
Minodronic acid hydrate is a novel bisphosphonate with stronger anti-resorptive effects, compared to the other existing bisphosphonates. We performed additional analyses of phase III clinical trial and compared the effect of minodronic acid hydrate on bone turnover markers with those of alendronate in primary osteoporosis. The results showed that minodronic acid hydrate suppressed bone turnover early after treatment, and it also was effective in the treatment of patients with prevalent vertebral fracture, which is a high risk for subsequent fracture.
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