病毒性表皮
细胞质
衣壳
免疫电镜
超微结构
生物
细胞生物学
病毒学
病毒
生物物理学
解剖
抗体
遗传学
作者
Shiro Nii,Fumio Uno,Minoru Yoshida,Kazuya Akatsuka
出处
期刊:PubMed
日期:1998-01-01
卷期号:56 (1): 22-8
被引量:6
摘要
This review is concerned with the structure and assembly of HCMV, HHV6 and HHV7. A characteristic ultrastructural feature common to all these viruses is a distinct tegumentary coating of intracytoplasmic capsids. The tegument structure is also distinctly seen in the virions of HHV6 and HHV7. Morphologically, acquisition of the tegument was observed to have taken place in the cytoplasm. Immunoelectron microscopic studies of HCMV infected cells, however, have demonstrated the existence of a tegument protein, pp150, on the surface of intranuclear capsids as well as on capsids in the cytoplasm and in extracellular virions. In addition, another tegument protein, pp65 has been detected within the matrix of cytoplasmic and extracellular dense bodies but not in virions. The molecular mechanism of the assembly of beta herpesviruses was also discussed.
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