3D打印
再生医学
药物输送
纳米技术
智能材料
3d打印
计算机科学
组织工程
再生(生物学)
3D生物打印
生物医学工程
材料科学
工程类
机械工程
化学
细胞生物学
生物
细胞
生物化学
作者
Qiqi Gao,Jaeseong Lee,Byoung Soo Kim,Ge Gao
出处
期刊:International Journal of bioprinting
[Whioce Publishing Pte Ltd.]
日期:2022-11-09
卷期号:9 (1): 638-638
被引量:12
标识
DOI:10.18063/ijb.v9i1.638
摘要
Three-dimensional (3D) printing, which is a valuable technique for the fabrication of tissue-engineered constructs and biomedical devices with complex architectures, has brought about considerable progress in regenerative medicine, drug delivery, and diagnosis of diseases. However, because of the static and inanimate properties of conventional 3D-printed structures, it is difficult to use them in therapies for active and precise medicine, such as improved tissue regeneration, targeted or controlled drug delivery, and advanced pathophysiological monitoring. The integration of stimuli-responsive biomaterials into 3D printing provides a potential strategy for designing and building smart constructs that exhibit programmed functions and controllable changes in properties in response to exogenous and autogenous stimuli. These features make 3D-printed smart constructs the next generation of tissue-engineered products. In this review, we introduce the prevalent 3D printing techniques (with an emphasis on the differences between 3D printing and bioprinting, and biomaterials and bioink), the working principle of each technique, and the advantages of using 3D printing for the fabrication of smart constructs. Stimuli-responsive biomaterials that are widely used for 3D printing of smart constructs are categorized, followed by a summary of their applications in tissue regeneration, drug delivery, and biosensors. Finally, the challenges and future perspectives of 3D-printed smart constructs are discussed.
科研通智能强力驱动
Strongly Powered by AbleSci AI