单胺氧化酶
化学
苯丙素
酶
单胺类神经递质
生物化学
生物合成
血清素
受体
作者
Chengcheng Hui,Shuaibo He,Miaomiao Ji,Y.-H. Percival Zhang,Haibo Wang,Xiao‐Wei Wang,Tailiang Guo
标识
DOI:10.1002/cbdv.202400524
摘要
Baihe is a commonly used Chinese medicine for the treatment of neurological disorders. Clinically, the bulbs of Lilium brownii are used to act as Baihe. In the study, two new phenylpropanoid compounds including 3-O-acetyl-1-O-caffeoylglycerol (1) and 3-O-acetyl-1-O-p-coumaroylglycerol (2) were isolated from the bulbs of L. brownii. Their structures were identified by spectroscopic method and the effect on monoamine oxidase activity was determined using an enzyme labeling method. The results show 1 and 2 have anti-monoamine oxidase activity with 20.96% and 22.31% inhibition rates at 50 μg/ml, respectively.
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