Global incidence and mortality of severe fungal disease

We read, with great interest, David W Denning's estimates on the global incidence and mortality of severe fungal disease.1 We agree there is a crucial need for accurate estimates of fungal diseases, the absence of which contribute to a lack of awareness, underdiagnosis, equity concerns, and inadequate research funding. However, we have several concerns with the estimation approach and representation of estimates presented in the study.