药效学
小檗碱
药理学
PI3K/AKT/mTOR通路
蛋白激酶B
代谢组
胰岛素受体
代谢组学
化学
生物化学
胰岛素
信号转导
生物
胰岛素抵抗
药代动力学
生物信息学
内分泌学
作者
Wenjuan Ma,Jianglan Long,Linjie Dong,Jian Zhang,Aiting Wang,Yu Zhang,Dan Yan
标识
DOI:10.1016/j.jep.2024.117752
摘要
Xiaoke formulation (XKF) has been utilized in clinical practice for decades in China as a treatment option for mild to moderate type 2 diabetes. However, there is still a need for systematic research to uncover the key pharmacodynamic material basis and mechanism of XKF.
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