Environmental toxicants modulate disease severity in pediatric metabolic dysfunction‐associated steatohepatitis
医学
脂肪性肝炎
疾病
疾病严重程度
内科学
脂肪肝
作者
Ajay K. Jain,Stefanie A. Busgang,Chris Gennings,Katherine P. Yates,Jeffrey B. Schwimmer,Philip J. Rosenthal,Karen F. Murray,Jean P. Molleston,Ann Scheimann,Stavra A. Xanthakos,Cynthia Behling,Danielle Carpenter,Mark Fishbein,Brent A. Neuschwander‐Tetri,James Tonasia,Miriam B. Vos
Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in children. We hypothesized environmental toxins could drive progression to metabolic dysfunction-associated steatohepatitis (MASH), and assayed serum toxins and metabolites in children with histologically characterized MASLD/MASH.
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