Right Ventricular Response to Cardiac Resynchronization Therapy: A Three-Dimensional and Speckle Tracking Echocardiographic Study

医学 心脏病学 内科学 心脏再同步化治疗 射血分数 心室 斑点追踪超声心动图 心力衰竭 反流(循环)
作者
Moustafa Dawood,Eman Elsharkawy,Moustafa Nawar,Mohamed Sanhoury
出处
期刊:American Journal of Cardiology [Elsevier BV]
卷期号:205: 150-161 被引量:3
标识
DOI:10.1016/j.amjcard.2023.07.105
摘要

Cardiac resynchronization therapy (CRT) induces left ventricle reverse remodeling; however, its effects on right ventricular (RV) volumes and function were not well described. This study aimed to assess the effects of CRT on RV. Of 112 patients, 63 enrolled with a mean age of 62.77 ± 7.23 years, including 40 males (63.5%). All patients met criteria for CRT implantation and were followed at 3-month and 6-month intervals. Standard 2-dimensional/3-dimensional (3D) echocardiography and speckle-tracking analyses were conducted for assessment of LV and left atrium (LA). RV maximum diameters, tricuspid lateral annular systolic velocity, tricuspid annular plane systolic excursion, fractional area change, RV global (RV 4-chamber strain (RV4CSL), and RV free wall strain (RVFWSL), in addition to 3D echocardiographic assessment of RV, were done before CRT implantation and at follow-up visits. Mean follow-up period was 6.76 ± 1.25 months. A total of 48 patients (76.2%) were LV responders (LVR) whereas the rest were nonresponders (LVNR). Both groups had similar baseline characteristics, risk factors, device implantation, and programming values. Only LVR had significant reduction in RV basal diameter, together with significant improvement of RV systolic performance: systolic velocity, fractional area change, RV4CSL, RVFWSL, and 3D-derived RV volumes and ejection fraction, compared with baseline values. In addition, pulmonary arterial systolic pressure decreased in LVR with reduction of tricuspid regurgitation severity. LV response, percentage change of RV4CSL, LA end-systolic volume index, and LA emptying fraction at 3-month follow-up were the most independent predictors of RV response by multivariate analysis. Reduced left ventricular end-systolic volume >13.5% had 92.3% sensitivity and 81.8% specificity. In conclusion, CRT-induced RV reverse remodeling and improved RV-arterial coupling. These effects were associated with left side response to CRT.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
略略略完成签到 ,获得积分10
5秒前
支雨泽完成签到,获得积分10
7秒前
小冯完成签到 ,获得积分10
9秒前
孙燕应助耐凡不哭采纳,获得80
10秒前
15秒前
四夕完成签到 ,获得积分10
16秒前
lilylwy完成签到 ,获得积分0
17秒前
日上三竿完成签到 ,获得积分10
20秒前
CYT完成签到,获得积分10
21秒前
无敌暴龙战神完成签到,获得积分10
22秒前
上进完成签到 ,获得积分10
26秒前
拼搏的白云完成签到,获得积分10
31秒前
昂莫达完成签到 ,获得积分10
31秒前
蛋花肉圆汤完成签到,获得积分10
32秒前
隐形的飞珍完成签到,获得积分10
33秒前
木头完成签到,获得积分10
37秒前
安静严青完成签到 ,获得积分10
43秒前
小花生完成签到 ,获得积分10
46秒前
忧伤的八宝粥完成签到 ,获得积分0
51秒前
xiaofeng5838完成签到,获得积分10
52秒前
靓丽的熠彤完成签到,获得积分10
53秒前
搜集达人应助lianqing采纳,获得10
53秒前
53秒前
瑾玉完成签到,获得积分10
54秒前
温暖的小鸭子完成签到,获得积分10
55秒前
SciKid524完成签到 ,获得积分10
59秒前
开拖拉机的医学僧完成签到 ,获得积分10
1分钟前
整齐百褶裙完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
奥丁蒂法完成签到,获得积分10
1分钟前
liu完成签到 ,获得积分10
1分钟前
1分钟前
kryptonite完成签到 ,获得积分10
1分钟前
嘻嘻完成签到 ,获得积分10
1分钟前
排骨炖豆角完成签到 ,获得积分10
1分钟前
qw1完成签到,获得积分20
1分钟前
1分钟前
1分钟前
lianqing发布了新的文献求助10
1分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 370
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990992
求助须知:如何正确求助?哪些是违规求助? 3532247
关于积分的说明 11256757
捐赠科研通 3271164
什么是DOI,文献DOI怎么找? 1805331
邀请新用户注册赠送积分活动 882302
科研通“疑难数据库(出版商)”最低求助积分说明 809236