外体
微泡
纳米技术
药物输送
生物技术
基因传递
生物医学
计算生物学
生物
生化工程
遗传增强
工程类
生物信息学
材料科学
小RNA
基因
生物化学
作者
Min Cao,Ningning Diao,Xiaolu Cai,Xing Chen,Yi Xiao,Chunjing Guo,Daquan Chen,Xingcai Zhang
出处
期刊:Materials horizons
[The Royal Society of Chemistry]
日期:2023-01-01
卷期号:10 (10): 3879-3894
被引量:29
摘要
Natural plants have been attracting increasing attention in biomedical research due to their numerous benefits. Plant exosome-derived vesicles, some of the plant's components, are small nanoscale vesicles secreted by plant cells. These vesicles are rich in bioactive substances and play significant roles in intercellular communication, information transfer, and maintaining homeostasis in organisms. They also hold promise for treating diseases, and their vesicular structures make them suitable carriers for drug delivery, with large-scale production feasible. Therefore, this paper aims to provide an overview of nanovesicles from different plant sources and their extraction methods. We also outline the biological activities of nanovesicles, including their anti-inflammatory, anti-viral, and anti-tumor properties, and systematically introduce their applications in drug delivery. These applications include transdermal delivery, targeted drug delivery, gene delivery, and their potential use in the modern food industry. This review provides new ideas and methods for future research on plant exosomes, including their empowerment by artificial intelligence and gene editing, as well as their potential application in the biomedicine, food, and agriculture industries.
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