小发夹RNA
癌症研究
肿瘤微环境
免疫系统
免疫疗法
RNA甲基化
CD8型
免疫检查点
基因沉默
生物
免疫学
基因敲除
细胞培养
甲基化
生物化学
遗传学
甲基转移酶
基因
作者
Yonghua Tong,Zhiqiang Chen,Jian Wu,Qiu Huang,Yu He,Haojie Shang,Xia Ding,Ejun Peng,Zhihua Wang,Xiaoyu Liang,Kun Tang
标识
DOI:10.1136/jitc-2024-011108
摘要
These findings highlight METTL3 as a key regulator of the immune microenvironment in BLCA and a promising therapeutic target to improve immunotherapy outcomes. Targeting METTL3 could potentially enhance the efficacy of ICIs in patients with BLCA.
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