围手术期
医学
观察研究
机械通风
重症监护医学
心胸外科
麻醉
肺
入射(几何)
外科
内科学
光学
物理
作者
Ben Shelley,Nándor Marczin
标识
DOI:10.1016/j.bja.2022.07.017
摘要
The concept, mechanisms, and physical and physiological determinants of ventilator-induced lung injury, as well as the influence of lung-protective ventilation strategies, are novel paradigms of modern intensive care and perioperative medicine. Driving pressure and mechanical power have emerged as meaningful and modifiable targets with specific relevance to thoracic anaesthesia and one-lung ventilation. The relationship between these factors and postoperative pulmonary complications remains complex because of the methodological design and outcome selection. Larger observational studies are required to better understand the characteristics of driving pressure and power in current practice of thoracic anaesthesia in order to design future trials in high-risk thoracic populations at risk of acute lung injury.
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