Reproducibility and Treatment Effect on Office and Ambulatory Pressure Relation

回廊的 医学 指南 血压 线性回归 动态血压 舒张期 内科学 隐匿性高血压 拉西地平 心脏病学 再现性 物理疗法 统计 数学 病理 受体 敌手
作者
Giuseppe Mancia,Rita Facchetti,Fosca Quarti‐Trevano,Guıdo Grassı
出处
期刊:Hypertension [Lippincott Williams & Wilkins]
被引量:1
标识
DOI:10.1161/hypertensionaha.124.23549
摘要

BACKGROUND: In the absence of outcome-based ambulatory blood pressure (BP) data hypertension guidelines provide 24-hour mean BP values corresponding to trial-validated office BP values. Data are shown for untreated and treated patients together, but whether corresponding ambulatory values are similar in untreated and treated hypertensives and reproducible at yearly measurements during treatment is undefined. METHODS: In 2397 patients of the ELSA (European Lacidipine Study on Atherosclerosis) and PHYLLIS (Plaque Hypertension Lipid-Lowering Italian Study) trials, we calculated the office and 24-hour BP relationship according to the linear regression model, with office systolic BP as the independent variable, at baseline and yearly during a 3-year treatment. Twenty-four hour BP values corresponding to clinically important office BP values (hypertension grades and treatment thresholds and targets) were calculated and compared with those provided by guidelines. RESULTS: Office/24-hour systolic BP or diastolic BP always exhibited a significant linear relationship, with, however, limited Pearson correlation coefficients (never >0.44).The slopes of the relationship were superimposable between different years of treatment but always significantly less steep than the slope seen in untreated individuals. Compared with the guideline-provided corresponding values, 24-hour BP showed qualitative and quantitative differences; for example, it was considerably lower and higher than the guideline-corresponding values when office BP was in the high hypertension and low treatment target ranges, respectively. CONCLUSIONS: In treated patients with hypertension the slope of the office/24-hour BP linear regression is reproducible over time. However, the slopes are steeper in untreated individuals, indicating that information on ambulatory BP values corresponding to office BP values can be more accurate if separately estimated in these 2 conditions.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
希望天下0贩的0应助雪碧采纳,获得10
1秒前
爆米花应助科研通管家采纳,获得10
2秒前
坦率的匪应助科研通管家采纳,获得10
2秒前
2秒前
隐形曼青应助科研通管家采纳,获得10
2秒前
pcr163应助科研通管家采纳,获得80
2秒前
大模型应助科研通管家采纳,获得30
2秒前
Jasper应助科研通管家采纳,获得10
2秒前
大个应助科研通管家采纳,获得10
2秒前
科研通AI5应助舒服的乐曲采纳,获得10
2秒前
传奇3应助科研通管家采纳,获得10
2秒前
坦率的匪应助科研通管家采纳,获得10
2秒前
汉堡包应助科研通管家采纳,获得10
2秒前
2秒前
坦率的匪应助科研通管家采纳,获得10
2秒前
2秒前
quhayley应助科研通管家采纳,获得10
2秒前
要减肥岩应助科研通管家采纳,获得10
3秒前
彭于彦祖应助培爷采纳,获得30
3秒前
Mininine完成签到,获得积分10
3秒前
3秒前
Akim应助科研通管家采纳,获得10
3秒前
quhayley应助科研通管家采纳,获得10
3秒前
LUJyyyy完成签到,获得积分10
3秒前
SciGPT应助科研通管家采纳,获得10
3秒前
爆米花应助科研通管家采纳,获得10
3秒前
3秒前
SYLH应助科研通管家采纳,获得50
4秒前
JamesPei应助科研通管家采纳,获得10
4秒前
完美世界应助科研通管家采纳,获得10
4秒前
我是老大应助科研通管家采纳,获得10
4秒前
SYLH应助科研通管家采纳,获得50
4秒前
华仔应助科研通管家采纳,获得10
4秒前
坦率的匪应助科研通管家采纳,获得10
4秒前
领导范儿应助科研通管家采纳,获得10
4秒前
彭于晏应助科研通管家采纳,获得10
4秒前
4秒前
4秒前
5秒前
华仔应助Yy采纳,获得10
6秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988732
求助须知:如何正确求助?哪些是违规求助? 3531027
关于积分的说明 11252281
捐赠科研通 3269732
什么是DOI,文献DOI怎么找? 1804764
邀请新用户注册赠送积分活动 881869
科研通“疑难数据库(出版商)”最低求助积分说明 809021