易普利姆玛
无容量
危险系数
医学
肿瘤科
临床终点
置信区间
阶段(地层学)
佐剂
新辅助治疗
辅助治疗
随机化
内科学
外科
随机对照试验
化疗
免疫疗法
癌症
乳腺癌
生物
古生物学
作者
Christian U Blank,Minke W Lucas,Richard A. Scolyer,Bart A van de Wiel,Alexander M Menzies,Marta Lopez-Yurda,Lotte L Hoeijmakers,Robyn P M Saw,Judith M Lijnsvelt,Nigel G Maher,Saskia M Pulleman,Maria Gonzalez,Alejandro Torres Acosta,Winan J. van Houdt,Serigne N Lo,Anke M J Kuijpers,Andrew Spillane,W Martin C Klop,Thomas E Pennington,Charlotte L Zuur
标识
DOI:10.1056/nejmoa2402604
摘要
Among patients with resectable, macroscopic stage III melanoma, neoadjuvant ipilimumab plus nivolumab followed by surgery and response-driven adjuvant therapy resulted in longer event-free survival than surgery followed by adjuvant nivolumab. (Funded by Bristol Myers Squibb and others; NADINA ClinicalTrials.gov number, NCT04949113.).
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