茉莉酸
转录因子
茉莉酸甲酯
细胞生物学
植物对草食的防御
生物合成
生物
基因表达调控
基因表达
抄写(语言学)
生物化学
防御机制
基因
信号转导
植保素
化学
拟南芥
白藜芦醇
突变体
哲学
语言学
作者
Wen‐Kai Wu,Gui‐Bin Nie,Jia‐Ling Lin,Jia‐Fa Huang,Xiao‐Xiang Guo,Mei Chen,Xin Fang,Ying‐Bo Mao,Yan Li,Ling‐Jian Wang,Xiaoyuan Tao,Yi‐Qun Gao,Zuoren Yang,Jinquan Huang
标识
DOI:10.1002/advs.202403059
摘要
Abstract Plants have evolved diverse defense mechanisms encompassing physical and chemical barriers. Cotton pigment glands are known for containing various defense metabolites, but the precise regulation of gland size to modulate defense compound levels remains enigmatic. Here, it is discovered that the VQ domain‐containing protein JAVL negatively regulates pigment gland size and the biosynthesis of defense compounds, while the MYC2‐like transcription factor GoPGF has the opposite effect. Notably, GoPGF directly activates the expression of JAVL , whereas JAVL suppresses GoPGF transcription, establishing a negative feedback loop that maintains the expression homeostasis between GoPGF and JAVL . Furthermore, it is observed that JAVL negatively regulates jasmonate levels by inhibiting the expression of jasmonate biosynthetic genes and interacting with GoPGF to attenuate its activation effects, thereby maintaining homeostatic regulation of jasmonate levels. The increased expression ratio of GoPGF to JAVL leads to enlarged pigment glands and elevated jasmonates and defense compounds, enhancing insect and pathogen resistance in cotton. These findings unveil a new mechanism for regulating gland size and secondary metabolites biosynthesis, providing innovative strategies for strengthening plant defense.
科研通智能强力驱动
Strongly Powered by AbleSci AI