透明质酸
多粘菌素B
肺炎
多粘菌素
细菌
脂多糖
抗生素
化学
微生物学
炎症
生物
医学
免疫学
内科学
遗传学
解剖
作者
Peisen Zhang,Qiuhong Ouyang,Tianshu Zhai,Jing Sun,Jun Wu,Feng Qin,Ni Zhang,Saisai Yue,Xinchen Yang,Hanyi Zhang,Yi Hou,Deng Li,Fang Wang,Qingyuan Zhan,Qingsong Yu,Meng Qin,Zhihua Gan
出处
期刊:Nanoscale
[The Royal Society of Chemistry]
日期:2022-01-01
卷期号:14 (41): 15291-15304
被引量:16
摘要
PMB-HA nanoparticles constructed by self-assembly of hyaluronic acid and polymyxin B can precisely target the CD44 receptors over-expressed in pneumonia region and kill bacteria through the competitive binding of polymyxin B and lipopolysaccharide.
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