CD8型
生物
MHC I级
主要组织相容性复合体
MHC II级
细胞毒性T细胞
树突状细胞
干扰素
免疫
免疫学
癌症研究
交叉展示
抗原
免疫系统
体外
遗传学
作者
Ellen Duong,Tim Fessenden,Emi A. Lutz,Teresa Dinter,Leon Yim,Sarah E. Blatt,Arjun Bhutkar,K. Dane Wittrup,Stefani Spranger
出处
期刊:Immunity
[Elsevier]
日期:2021-11-19
卷期号:55 (2): 308-323.e9
被引量:186
标识
DOI:10.1016/j.immuni.2021.10.020
摘要
Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor immunity. To delineate the DC states associated with productive anti-tumor T cell immunity, we compared spontaneously regressing and progressing tumors. Tumor-reactive CD8
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