医学
放射科
甲状腺乳突癌
甲状腺癌
转移
淋巴
核医学
淋巴结
甲状腺癌
颈淋巴结
置信区间
癌
甲状腺
癌症
病理
内科学
作者
Ayşegül Gürsöy Çoruh,Çağlar Uzun,Melahat Kul,Zehra Akkaya,Atilla Halil Elhan,Kürşat Gökcan
出处
期刊:Journal of Computer Assisted Tomography
[Ovid Technologies (Wolters Kluwer)]
日期:2020-03-01
卷期号:44 (2): 262-268
被引量:8
标识
DOI:10.1097/rct.0000000000001005
摘要
Objective The purpose of this study was to assess the diagnostic performance of multiphasic computed tomography (CT) in the discrimination of metastatic lymph nodes (LNs) of papillary thyroid cancer by using quantitative parameters. Methods This study enrolled 272 pathologically proven metastatic and benign LNs. Multiphasic CT was utilized by using nonenhanced, arterial (25-second delay), and venous (80-second delay) phases. Mean tissue attenuation values (MAVs) of metastatic and benign LNs were measured, and normalized MAV (common carotid artery and paraspinal muscle) and wash-in and wash-out percentages were also calculated. Results The arterial phase showed the highest diagnostic performance in differentiation (area under the curve ± standard error, 0.97 ± 0.02; 95% confidence interval, 0.94–1.0; P < 0.001). Cutoff values for MAVs, normalized MAVs, and wash-in and wash-out percentages to predict metastatic LNs were calculated as 109 HU, 0.33, 1.93, 122.5, and −5.6 (sensitivity: 93.4%, 93.3%, 90.4%, 94.1%, and 97.8%, and specificity: 99.3%, 90.4%, 98.5%, 92.6%, and 99.3%, respectively). Conclusions Early-phase enhanced CT and the use of quantitative parameters derived from multiphasic CT improve the detection of cervical lymph node metastasis from papillary thyroid cancer.
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