亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

P3-287: NEUROPSYCHOLOGICAL FACTORS PREDICTING REVERSION FROM MILD COGNITIVE IMPAIRMENT TO COGNITIVELY NORMAL: 1 YEAR FOLLOW-UP STUDY

神经心理学 复归 认知障碍 听力学 心理学 认知 临床心理学 医学 精神科 生物化学 化学 基因 表型
作者
Ji Yeon Chung,Hye-Young Yoon,Hoowon Kim,Il Han Choo,Kyu Yeong Choi,Jang Jae Lee,Kun Ho Lee,Eun Hyun Seo
出处
期刊:Alzheimers & Dementia [Wiley]
卷期号:15: P1047-P1047
标识
DOI:10.1016/j.jalz.2019.06.3318
摘要

Little attention has been given to the meaning of reversion from mild cognitive impairment (MCI) to cognitively normal (CN) and predictive factors associated with such reversion. The purpose of the study was to clarify underlying causes for reversion from MCI to CN and to identify factors associated with reversion. We carefully included 200 individuals with MCI who were likely to be in Alzheimer's disease (AD) spectrum controlling for other etiologies, and reassessed at a subsequent visit about 1.5 year later. All participants underwent comprehensive clinical and neuropsychological assessment. Associated factors with reversion were examined by t-test, χ2 test, and logistic regression. Longitudinal change was examined by a repeated measure ANOVA. Based on the second assessment, 78 (39%) were reverted to CN (rMCI), and 118 (59%) were stayed MCI (sMCI). Four (2%) were progressed to AD and they were excluded in the further analysis. Group difference was significant only in the neuropsychological tests assessing cognitive control ability among a wide range of socio-demographic, clinical, and neuropsychological variables. Both group showed improvement mainly in memory implying practice effect, but rMCI showed much greater improvement. This study preliminary suggest that reversion from MCI to CN might not be a false positive error but a true recovery from cognitive impairment, especially in memory domain. Our results imply that characteristics favorable to restoration of cognitive function may be higher cognitive control ability. Therefore, assessing cognitive control ability might facilitate developing appropriate interventions for MCI as well as prognosis evaluation.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
香蕉觅云应助科研通管家采纳,获得10
1秒前
15秒前
林宥嘉完成签到 ,获得积分10
19秒前
老夫子完成签到,获得积分10
21秒前
kenti2023完成签到 ,获得积分10
26秒前
42秒前
YYYCCCCC发布了新的文献求助10
51秒前
51秒前
11发布了新的文献求助10
56秒前
CipherSage应助miles采纳,获得10
59秒前
周游完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
huihongzeng发布了新的文献求助10
1分钟前
Judy完成签到 ,获得积分10
1分钟前
利物鸟贝拉完成签到,获得积分10
1分钟前
1分钟前
Esperanza完成签到,获得积分10
1分钟前
miles发布了新的文献求助10
1分钟前
1分钟前
鹿茸与共发布了新的文献求助10
1分钟前
1分钟前
jianghs完成签到,获得积分10
1分钟前
科目三应助11采纳,获得10
1分钟前
jianghs发布了新的文献求助10
1分钟前
1分钟前
feifei完成签到,获得积分10
1分钟前
feifei发布了新的文献求助10
1分钟前
福娃哇完成签到 ,获得积分10
1分钟前
科研通AI2S应助科研通管家采纳,获得10
2分钟前
科目三应助科研通管家采纳,获得10
2分钟前
2分钟前
草莓熊1215完成签到 ,获得积分10
2分钟前
青竹完成签到,获得积分10
2分钟前
旺仔先生完成签到 ,获得积分10
2分钟前
2分钟前
candy teen完成签到,获得积分10
2分钟前
垃圾桶完成签到 ,获得积分10
2分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990015
求助须知:如何正确求助?哪些是违规求助? 3532077
关于积分的说明 11256227
捐赠科研通 3270933
什么是DOI,文献DOI怎么找? 1805139
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228