Review question / Objective: P: Patients diagnosed with Hyperkalemia I: The experimental group was treated with Sodium Zirconium Cyclosilicate C: The control group was treated with placebo O: c h a n g e i n s e r u m p o t a s s i u m S : Ramdomized controlled studies.Condition being studied: Hyperkalemia is the most common electrolyte disturbance.Patients at the highest risk of hyperkalemia are those with chronic kidney disease and h e a r t f a i l u r e .s o d i u m z i r c o n i u m cyclosilicate is a highly selective cation exchanger that is not systemically adsorbed, entraps potassium in the gastrointestinal tract in exchange for INPLASY 1 International Platform of Registered Systematic Review and Meta-analysis Protocols INPLASY PROTOCOLThe Efficacy and safety of Sodium Zirconium Cyclosilicate for the treatment of Hyperkalemia: a meta-analysis of randomized controlled trials