抗真菌
喹啉
喹唑啉
抗寄生虫的
生物活性
化学
药理学
生物碱
生物
组合化学
医学
立体化学
生物化学
有机化学
微生物学
体外
病理
作者
Xiaofei Shang,Susan L. Morris‐Natschke,Guan‐Zhou Yang,Ying‐Qian Liu,Xiao Guo,Xiaoshan Xu,Masuo Goto,Juncai Li,Jiyu Zhang,Kuo‐Hsiung Lee
摘要
Abstract To follow‐up on our prior Part I review, this Part II review summarizes and provides updated literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009‒2016, together with the biological activity and the mechanisms of action of these classes of natural products. Over 200 molecules with a broad range of biological activities, including antitumor, antiparasitic and insecticidal, antibacterial and antifungal, cardioprotective, antiviral, anti‐inflammatory, hepatoprotective, antioxidant, anti‐asthma, antitussive, and other activities, are discussed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.
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