神经炎症
医学
神经保护
创伤性脑损伤
认知
神经科学
精神科
炎症
心理学
免疫学
药理学
作者
Molly Monsour,Davide Marco Croci,Siviero Agazzi
标识
DOI:10.1016/j.clineuro.2022.107280
摘要
This literature review focuses on the role of IL-6 in TBI or PTSD-induced neuroinflammation. While TBI and PTSD are widely prevalent, these diagnoses are particularly common amongst veterans. Given the role of IL-6 in neuroprotection acutely, compared to detrimental chronically, targeting this cytokine at specific time points may be beneficial in modulating neuroinflammation. Current treatments for TBI or PTSD are variably affective. By reviewing the role of IL-6 in these two diagnoses, future studies can focus on therapeutics to treat neuroinflammation and ultimately reduce the devastating impacts of neuroinflammation on cognition in PTSD and TBI.
科研通智能强力驱动
Strongly Powered by AbleSci AI