自身免疫
CD80
焦虑
免疫学
生物
细胞生物学
心理学
作者
Nathan A. Bracey,Jonathan S. Maltzman
出处
期刊:Science immunology
[American Association for the Advancement of Science (AAAS)]
日期:2022-04-01
卷期号:7 (70)
标识
DOI:10.1126/sciimmunol.abq1728
摘要
A monoclonal antibody targeting CD80 on antigen presenting cells disrupts cis-interactions with PD-L1, reviving T cell inhibitory checkpoint signaling to suppress autoimmunity.
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