Highly Efficient Reagents for Br/Mg Exchange

The conversion of electron-rich aryl bromides into the corresponding Grignard compounds proceeds within 2 h at 25 °C in the presence of 0.55 equivalents of the new reagent sBu2Mg⋅LiCl. The high reactivity of magnesiates is rationalized by quantum chemical model calculations, and selected examples illustrate the benefits of aryl magnesium compounds for organic syntheses. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502220_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.