The ultrasound characteristics of regions identified as suspicious by magnetic resonance imaging (MRI) predict the likelihood of clinically significant cancer on MRI–ultrasound fusion‐targeted biopsy

医学 磁共振成像 活检 前列腺癌 超声波 放射科 癌症 感兴趣区域 单变量分析 核医学 多元分析 内科学
作者
Benjamin Press,Andrew B. Rosenkrantz,Weiwei Huang,Samir S. Taneja
出处
期刊:BJUI [Wiley]
卷期号:123 (3): 439-446 被引量:8
标识
DOI:10.1111/bju.14615
摘要

Objective To determine whether the presence of an ultrasound hypoechoic region at the site of a region of interest ( ROI ) on magnetic resonance imaging ( MRI ) results in improved prostate cancer ( PC a) detection and predicts clinically significant PC a on MRI –ultrasonography fusion‐targeted prostate biopsy ( MRF ‐ TB ). Materials and Methods Between July 2011 and June 2017, 1058 men who underwent MRF ‐ TB , with or without systematic biopsy, by a single surgeon were prospectively entered into an institutional review board‐approved database. Each MRI ROI was identified and scored for suspicion by a single radiologist, and was prospectively evaluated for presence of a hypoechoic region at the site by the surgeon and graded as 0, 1 or 2, representing none, a poorly demarcated ROI‐HyR, or a well demarcated ROI‐HyR, respectively. The interaction of MRI suspicion score ( mSS ) and ultrasonography grade ( USG ), and the prediction of cancer detection rate by USG , were evaluated through univariate and multivariate analysis. Results For 672 men, the overall and Gleason score ( GS ) ≥7 cancer detection rates were 61.2% and 39.6%, respectively. The cancer detection rates for USG s 0, 1 and 2 were 46.2%, 58.6% and 76.0% ( P < 0.001) for any cancer, and 18.7%, 35.2% and 61.1% ( P < 0.001) for GS ≥7 cancer, respectively. For MRF ‐ TB only, the GS ≥7 cancer detection rates for USG 0, 1 and 2 were 12.8%, 25.7% and 52.0%, respectively ( P < 0.001). On univariate analysis, in men with mSS 2–4, USG was predictive of GS ≥7 cancer detection rate. Multivariable regression analysis showed that USG , prostate‐specific antigen density and mSS were predictive of GS ≥7 PC a on MRF ‐ TB . Conclusions Ultrasonography findings at the site of an MRI ROI independently predict the likelihood of GS ≥7 PC a, as men with a well‐demarcated ROI‐HyR at the time of MRF ‐ TB have a higher risk than men without.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
糟糕的梨愁完成签到,获得积分10
1秒前
莫西莫西完成签到 ,获得积分10
2秒前
小趴蔡完成签到 ,获得积分10
4秒前
唐唐发布了新的文献求助10
4秒前
飘逸剑身完成签到,获得积分10
7秒前
airtermis完成签到 ,获得积分10
7秒前
gfasdjsjdsjd完成签到,获得积分10
8秒前
8秒前
杨宁完成签到 ,获得积分10
8秒前
MchemG应助transition采纳,获得20
9秒前
科研通AI2S应助科研通管家采纳,获得10
10秒前
lxy发布了新的文献求助10
12秒前
gfasdjsjdsjd发布了新的文献求助10
13秒前
JCao727完成签到,获得积分10
13秒前
13秒前
14秒前
OAHCIL完成签到 ,获得积分10
15秒前
lixueao发布了新的文献求助10
16秒前
无辜的行云完成签到 ,获得积分0
19秒前
FIN应助gfasdjsjdsjd采纳,获得20
21秒前
今后应助gfasdjsjdsjd采纳,获得10
21秒前
排骨炖豆角完成签到 ,获得积分10
23秒前
一叶知秋应助大橙子采纳,获得10
25秒前
kk完成签到,获得积分10
28秒前
敏感春天完成签到,获得积分10
28秒前
凶狠的期待完成签到,获得积分10
30秒前
自然函发布了新的文献求助30
30秒前
JF123_完成签到 ,获得积分10
31秒前
量子星尘发布了新的文献求助10
31秒前
33秒前
杨召发布了新的文献求助10
34秒前
didi完成签到,获得积分10
34秒前
keyby发布了新的文献求助10
36秒前
FashionBoy应助xdc采纳,获得10
41秒前
杨召完成签到,获得积分10
46秒前
大橙子发布了新的文献求助10
50秒前
酷波er应助陈昊采纳,获得10
54秒前
hcsdgf完成签到 ,获得积分10
56秒前
可取完成签到,获得积分10
57秒前
zss完成签到 ,获得积分10
57秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038128
求助须知:如何正确求助?哪些是违规求助? 3575831
关于积分的说明 11373827
捐赠科研通 3305610
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022