Metabolism, Pharmacokinetics and Toxicity of Functional Groups

Drug targets and their structural motifs ADMET for the medicinal chemist Carboxlic acids and their isosteres Primary, secondary and tertiary amines and isosteres Sulphonamide as an essential group 1, 2 and 3 ring phenyl and heterocyclic cores Heterocycles and phenyls as essential pharmacophore groups Peptides and peptidomimetic cores Peptides and peptidomimetics as functional groups Transition state functions Alcohols and carbonyls Future targets and chemistry needs