增生性瘢痕
医学
伤口愈合
血管生成
增生
再生(生物学)
外科
病理
癌症研究
细胞生物学
生物
作者
Qian-Nan Zhao,Y M Zhou,Chen Sun
出处
期刊:Chinese journal of burns
日期:2021-06-20
卷期号:37 (6): 586-590
被引量:3
标识
DOI:10.3760/cma.j.cn501120-20200315-00167
摘要
Traumatic scar can not only exert influence on appearance and function of patients, but also affect psychological health status and life quality of patients to varying degrees. At present, scholars have confirmed from basic research that mechanical tension promotes the proliferation of inflammatory cells, fibroblasts, and other cells, as well as angiogenesis and epithelialization through a variety of mechanical conduction pathways and plays an important role in the formation of hypertrophic scar. Clinical studies have confirmed that surgical methods and adjuvant treatment to reduce the mechanical tension on wound can promote wound healing and inhibit hyperplasia of scar. This article summarizes the mechanism of hypertrophic scar formation, and surgical methods and adjunct means of reducing mechanical tension in traumatic wounds, aiming to provide a reference for reducing formation of hypertrophic scar in clinics.
科研通智能强力驱动
Strongly Powered by AbleSci AI