Safety Concerns for MOF Syntheses—Understanding the Behavior of DMF Mixtures at Elevated Temperature and Pressure

Herein we report how various metal–organic framework (MOF) reaction mixtures behave at elevated temperature and pressure. Adiabatic calorimetry and high-pressure differential scanning calorimetry experiments were conducted to probe the effect of excessive heating of these reaction mixtures to determine the safe working limits. These data demonstrate the safe working limits for certain reactions using DMF, metal, and linker mixtures.