原子力显微镜
表征(材料科学)
材料科学
共焦激光扫描显微镜
荧光
共焦
显微镜
壳聚糖
纳米技术
激光显微镜
光导原子力显微镜
导电原子力显微镜
共焦显微镜
荧光显微镜
化学工程
扫描共焦电子显微镜
扫描电子显微镜
光学
扫描电容显微镜
复合材料
生物医学工程
工程类
物理
医学
作者
Srinivas Mettu,Qianyu Ye,Meifang Zhou,Raymond R. Dagastine,Muthupandian Ashokkumar
出处
期刊:Soft Matter
[The Royal Society of Chemistry]
日期:2018-01-01
卷期号:14 (16): 3192-3201
被引量:13
摘要
Atomic Force Microscopy (AFM) is used to measure the stiffness and Young's modulus of individual microcapsules that have a chitosan cross-linked shell encapsulating tetradecane. The oil filled microcapsules were prepared using a one pot synthesis via ultrasonic emulsification of tetradecane and crosslinking of the chitosan shell in aqueous solutions of acetic acid. The concentration of acetic acid in aqueous solutions of chitosan was varied from 0.2% to 25% v/v. The effect of acetic acid concentration and size of the individual microcapsules on the strength was probed. The deformations and forces required to rupture the microcapsules were also measured. Three dimensional deformations of microcapsules under large applied loads were obtained by the combination of Laser Scanning Confocal Microscopy (LSCM) with Atomic Force Microscopy (AFM). The stiffness, and hence the modulus, of the microcapsules was found to decrease with an increase in size with the average stiffness ranging from 82 to 111 mN m-1 and average Young's modulus ranging from 0.4 to 6.5 MPa. The forces required to rupture the microcapsules varied from 150 to 250 nN with deformations of the microcapsules up to 62 to 110% relative to their radius, respectively. Three dimensional images obtained using laser scanning confocal microscopy showed that the microcapsules retained their structure and shape after being subjected to large deformations and subsequent removal of the loads. Based on the above observations, the oil filled chitosan crosslinked microcapsules are an ideal choice for use in the food and pharmaceutical industries as they would be able to withstand the process conditions encountered.
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