The role of preoperative breast magnetic resonance (MR) imaging for surgical decision in patients with triple-negative breast cancer.

医学 乳腺癌 乳房磁振造影 放射科 磁共振成像 乳腺摄影术 保乳手术
作者
Jeeyeon Lee,Jin Hyang Jung,Wan Wook Kim,Seung-Hyun Hwang,Hye Jung Kim,Ho Yong Park,Jin Ho Chung,Taek Ju Kwon,Yee Soo Chae,Soo Jung Lee,Jung Dug Yang,Jeong Woo Lee,Ji Young Park,Ji Yun Jeong
出处
期刊:Journal of Clinical Oncology [American Society of Clinical Oncology]
卷期号:34 (15_suppl): e12553-e12553
标识
DOI:10.1200/jco.2016.34.15_suppl.e12553
摘要

e12553 Background: Several reliable randomized studies do not recommend routine preoperative breast MR imaging for patients with breast cancer. However, because the principle of MR imaging is based on the dynamics of contrast enhancement, a specific biologic subgroup of tumors should sensitively respond to the imaging process. Methods: From 2008 to 2013, 918 eligible patients with breast cancer underwent breast surgery and were divided into two groups based on preoperative breast MR findings: patients in whom the surgical plan was changed and those in whom the surgical plan remained unchanged. We investigated the changing patterns of breast surgery based on routine mammography, ultrasound, and preoperative breast magnetic resonance (MR) findings and analyzed the association between additional suspicious lesions on breast MR imaging and clinicopathologic factors. Results: Additional suspicious breast lesions were detected on preoperative MR imaging in 104 cases (11.3%), and the surgical strategy was changed as the final decision in 97 cases (10.6%). There was no difference between oncologic results between two groups. However, the triple-negative breast cancer (TNBC) was significantly associated with changing of the surgical strategy based on breast MR findings (P= 0.048). Conclusions: Additional preoperative breast MR imaging may be helpful in surgical decision for patients with TNBC.

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