奥沙利铂
医学
养生
肿瘤科
化疗
持续时间（音乐）
结直肠癌
内科学
辅助化疗
辅助治疗
佐剂
阶段（地层学）
癌症
乳腺癌
古生物学
艺术
文学类
生物
作者
Axel Grothey,Alberto Sobrero,Anthony F. Shields,Takayuki Yoshino,James Paul,Julien Taı̈eb,John Souglakos,Qian Shi,Rachel Kerr,Roberto Labianca,Jeffrey A. Meyerhardt,Déwi Vernerey,Takeharu Yamanaka,Ioannis Boukovinas,Jeffrey P. Meyers,Lindsay A. Renfro,Donna Niedzwiecki,Toshiaki Watanabe,Valter Torri,Mark Saunders,Daniel J. Sargent,Thierry André,Timothy Iveson
标识
DOI：10.1056/nejmoa1713709
摘要
Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer. However, since oxaliplatin is associated with cumulative neurotoxicity, a shorter duration of therapy could spare toxic effects and health expenditures.
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