Study on Antioxidative Activity of Polysaccharide from Radix Hedysari in vitro

[Objective] The research aimed to study the antioxidant activity of polysaccharide HPS-3 from Radix Hedysari [Method] Under in vitro chemical simulated conditions,the scavenging effects of HPS-3's on superoxide anion(O-2·),hydroxyl radical (·OH),DPPH and H2O2 were measured for evaluating their antioxidant activity.[Result] The results showed that HPS-3 had some functions of scavenging free radicals,in the concentration range of 0.05-5.00 mg/ml.The maximum scavenging rate on O-2·,H2O2,·OH and DPPH were 55.92%,59.32%,53.69%,87.66% respectively and there was a dose-dependent relationship.[Conclusion] Polysaccharide from Radix Hedysari has distinctive antioxidant activity in vitro.