Study on the Recycling of 4-Chloro-6-methoxypyrimidine

4-Chloro-6-methoxypyrimidine(CMP) is a main by-product resulted in the production process of fungicide azoxystrobin.Recovery of CMP by reaction with bis(trichloromethyl)carbonate to the formation of 4,6dichloropyrimidine was developed.The optimal reaction conditions were obtained with the molar ratio of CMP to DMF and BTC to CMP were 1 to 3 and 1 to 1,respectively,and rthe reaction was run at 100℃ for two hours.The process has various advantages,including easy operation,environmentally friendly,good yields and convenient for scaled production.