材料科学
组织学
断层摄影术
生物医学工程
核医学
临床前影像学
碘
荧光
离体
医学影像学
计算机断层摄影术
荧光寿命成像显微镜
光学
体内
病理
放射科
医学
物理
生物技术
生物
冶金
作者
Shaozhou Pu,Yunwen Huang,Ning Zhao,Hui Liu,Yang Zuo,Chenghang Zheng,Hangcheng Zhou,Lei Zhu,Yidong Yang
出处
期刊:Optics Letters
[The Optical Society]
日期:2022-05-20
卷期号:47 (12): 3087-3087
被引量:1
摘要
An in-house dual-modality x-ray fluorescence tomography (XFT) and x-ray computed tomography (XCT) system was developed to quantify iodine contrast distribution through the whole tumor volume ex vivo. The quantitative XFT was calibrated with water phantoms containing iodine solutions of various concentrations (0.0175-1.4 wt.%). The vasculature distribution was reflected by the iodine perfusion, which was validated with histology. This technique may open a new, to the best of our knowledge, route to the non-destructive three-dimensional-imaging-based histological analysis of tumor samples.
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