Custom design and biomechanical clinical trials of 3D‐printed polyether ether ketone femoral shaft prosthesis

假肢 偷看 3d打印 股骨 材料科学 聚醚醚酮 生物医学工程 股管 口腔正畸科 外科 医学 复合材料 聚合物
作者
Chao Wu,Baifang Zeng,Jiayan Deng,Danwei Shen,Xiangyu Wang,Lun Tan,Xin Liu,Guigang Qiu
出处
期刊:Journal of Biomedical Materials Research Part B [Wiley]
卷期号:110 (9): 2006-2014 被引量:6
标识
DOI:10.1002/jbm.b.35055
摘要

During the surgical resection and reconstruction of a pathological femoral fracture, the removal of the femoral tumor leaves a large bone defect. Thus, it is necessary to reconstruct the defect and perform internal fixation. Polyether ether ketone (PEEK) has been widely used in spinal fusion and cranioplasty given its excellent biomechanical properties, biocompatibility, and stability. The typical design method of femoral prosthesis is based on the contralateral mirror image model (M-model), and we propose a novel method for designing femoral prosthesis, which is based on the cross section and centerline of the mirrored femur (C-model). In this study, the femoral shaft prostheses based on two models were manufactured using fused deposition modeling technology, and we use mechanical test and finite element analysis (FEA) to reveal the differences in mechanical properties of the two models. The mechanical results showed that the maximum loading force and yield strength were increased by 3% and 6% in the C-model prosthesis compared with the M-model prosthesis, respectively. In FEA, the results indicate that the C-model prosthesis could reduce the stress concentration by 5.4%-10.9% compared to the M-model prosthesis. Finally, the 3D-printed PEEK femoral shaft prosthesis based on C-model was implanted, no early complications occurred. Postoperative radiological examination indicated that the prosthesis and the femoral osteotomy end were closely matched and fixed well.
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