Systematic review with meta-analysis: effects of probiotic fungi on irritable bowel syndrome

肠易激综合征 益生菌 医学 科克伦图书馆 荟萃分析 系统回顾 随机对照试验 临床试验 内科学 重症监护医学 梅德林 生物 遗传学 生物化学 细菌
作者
Q. Qing,Ye Chen,Dekai Zheng,M.L. Sun,Yuanliang Xie,S.H. Zhang
出处
期刊:Beneficial Microbes [Wageningen Academic Publishers]
卷期号:14 (4): 303-315
标识
DOI:10.1163/18762891-20220134
摘要

Abstract Treatment of irritable bowel syndrome (IBS) remains challenging for clinicians. Probiotic fungi may act as candidate options for IBS treatment, but systematic evaluation of their clinical value remains scarce. This study is aimed to assess the efficacy and the safety of probiotic fungi for IBS treatment by means of systematic review and meta-analysis. PubMed, Embase, Web of Science, and the Cochrane Library, were searched up to June 2022. Randomised controlled trials recruited subjects with prescriptions of probiotic fungi were eligible. Efficacy and safety of probiotic fungi were re-evaluated. Continuous data were pooled to obtain standardised difference in means (SMD) with a 95% confidence interval. The search strategy identified 120 articles of which 7 trial assessing 883 subjects were included in the analysis. Systematic data support that Saccharomyces helps to relieve abdominal pain/discomfort (SMD = −0.205, ), and presented potential improvements on psychological outcomes, stool form for IBS patients. It is hard to demonstrate favourable effects on other symptoms (including distension, mucus passage, sense of incomplete evacuation, urgency, straining). The incidence of mild complications ranged from 0 to 51.4%, but no serious complications were observed in the included trials. Therefore, the partial response and the relative safe of probiotic fungi for IBS treatment have been demonstrated from the existing trials. However, it is premature to eventually declare the practical effects of probiotic fungi. Conducting more high-quality and large-scale trials and real-world studies, or even developing new fungal strains, is still necessary.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
领导范儿应助shixia采纳,获得10
刚刚
刚刚
ddz发布了新的文献求助10
刚刚
1秒前
爻炚完成签到 ,获得积分10
3秒前
彭于晏应助饭饱饱采纳,获得10
5秒前
7秒前
ddz完成签到,获得积分10
7秒前
充电宝应助金权富贵采纳,获得10
8秒前
9秒前
XL完成签到,获得积分20
10秒前
开心枫完成签到,获得积分10
13秒前
13秒前
roselin26完成签到,获得积分10
14秒前
14秒前
星辰大海应助汛钥采纳,获得10
14秒前
16秒前
树懒发布了新的文献求助10
16秒前
16秒前
烟花应助wbh采纳,获得10
16秒前
17秒前
脑洞疼应助庄大金采纳,获得10
18秒前
CipherSage应助科研通管家采纳,获得10
19秒前
今后应助科研通管家采纳,获得10
19秒前
烟花应助科研通管家采纳,获得10
19秒前
科研通AI2S应助科研通管家采纳,获得10
19秒前
科研通AI2S应助科研通管家采纳,获得10
20秒前
李健应助科研通管家采纳,获得10
20秒前
CipherSage应助科研通管家采纳,获得10
20秒前
所所应助科研通管家采纳,获得10
20秒前
英姑应助科研通管家采纳,获得10
20秒前
miao应助科研通管家采纳,获得60
20秒前
cindy应助科研通管家采纳,获得10
20秒前
科研通AI2S应助科研通管家采纳,获得10
20秒前
21秒前
枇杷发布了新的文献求助10
21秒前
22秒前
小菜完成签到 ,获得积分10
24秒前
葡萄树发布了新的文献求助10
25秒前
李朝富完成签到,获得积分10
26秒前
高分求助中
The ACS Guide to Scholarly Communication 2500
Sustainability in Tides Chemistry 2000
Microlepidoptera Palaearctica, Volumes 1 and 3 - 13 (12-Volume Set) [German] 1122
The Data Economy: Tools and Applications 1000
Diamonds: Properties, Synthesis and Applications 800
PraxisRatgeber Mantiden., faszinierende Lauerjäger. – Buch gebraucht kaufen 700
Mantiden - Faszinierende Lauerjäger – Buch gebraucht kaufen 700
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3096435
求助须知:如何正确求助?哪些是违规求助? 2748408
关于积分的说明 7599570
捐赠科研通 2400094
什么是DOI,文献DOI怎么找? 1273377
科研通“疑难数据库(出版商)”最低求助积分说明 615726
版权声明 598973