哌嗪
哌啶
苯并咪唑
药效团
化学
组合化学
药理学
生物
有机化学
立体化学
作者
Ajayrajsinh R. Zala,Premlata Kumari
标识
DOI:10.1002/slct.202301304
摘要
Abstract Nitrogen‐containing benzimidazole, piperazine, and piperidine are significant pharmacophores in medicinal chemistry and drug development. Many medications, lead compounds, and various reagents have these N‐containing scaffolds. This review concentrated on the development of novel therapeutic agents as well as the broad range of pharmacological actions demonstrated by benzimidazole, piperazine, and piperidine hybrids. The review emphasizes these hybrids′ potential, range, and medical significance. The review also discusses the structural criteria for benzimidazole, piperazine, and piperidine hybrids created by diverse chemists to be physiologically effective against a variety of disorders.
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