氧自由基吸收能力
Zeta电位
分散性
抗氧化剂
化学
脂质体
粒径
色谱法
花萼
吸光度
DPPH
纳米颗粒
生物化学
有机化学
材料科学
纳米技术
植物
物理化学
生物
作者
Elizabeth TOBAR-DELGADO,Oswaldo Osorio,Álvaro Barrera-Ocampo,Liliana Serna-Cock,Constaín H. Salamanca
标识
DOI:10.1016/j.colsurfb.2023.113662
摘要
The focus of this study was on the development, physicochemical characterisation and evaluation of the antioxidant activity of cape gooseberry calyx extract loaded into nanoliposomal systems. Various nanoliposomes were prepared and optimised using the ethanol injection method and characterised based on particle size, polydispersity and zeta potential measurements. Subsequently, the encapsulation efficiency and in vitro release profile of the natural antioxidant extract (NAE) were evaluated, and its antioxidant activity was assessed using the oxygen radical absorbance capacity assay. The results revealed that NAE-loaded nanoliposomes described desired quality features (e.g., particle size of < 200 nm, polydispersity index of < 0.3, zeta potential of > -40 mV and encapsulation efficiency of ∼70%). Furthermore, it was found that NAE release is controlled by various stages, and its antioxidant activity improves by around 30% when loaded into the nanoliposomes, suggesting that it could be a promising antioxidant functional raw material.
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