化学
硝化作用
嘌呤
催化作用
组合化学
有机化学
酶
作者
Yiwen Chen,Jianhui Liu,Xiguang Liu,Zhongkai Jiang,Shaorong Wang,Yixing Zhang,Mingwu Yu
标识
DOI:10.1016/j.tetlet.2024.154959
摘要
A late-stage, green and practical preparation of 6-(ortho-nitroaryl) amino purine derivatives was reported by using t-BuONO as the nitrating agent without transition-metal catalysts under air conditions. This method tolerates a wide variety of functional groups and is applicable for the gram scale synthesis, which may prove instrumental for further application in biochemistry. Preliminary mechanism was proposed through a series of experiments.
科研通智能强力驱动
Strongly Powered by AbleSci AI