细胞外基质
细胞生物学
血管平滑肌
硫氧化物9
化学
机械转化
机械敏感通道
生物
转录因子
内分泌学
生物化学
离子通道
基因
受体
平滑肌
作者
Maria Faleeva,Sadia Ahmad,Konstantinos Theofilatos,Steven Lynham,Gabriel Watson,Meredith Whitehead,Emilie Marhuenda,Thomas Iskratsch,Susan Cox,Catherine M. Shanahan
出处
期刊：Circulation Research
[Lippincott Williams & Wilkins]
日期：2024-02-01
卷期号：134 (3): 307-324
被引量：23
标识
DOI：10.1161/circresaha.123.323365
摘要
Vascular calcification and increased extracellular matrix (ECM) stiffness are hallmarks of vascular aging. Sox9 (SRY-box transcription factor 9) has been implicated in vascular smooth muscle cell (VSMC) osteo/chondrogenic conversion; however, its relationship with aging and calcification has not been studied.
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