[10-Methacryloyloxydecyl dihydrogen phosphate in resin-to-zirconia bonding durability: a systematic review and meta-analysis].

Objective: To systematically assess the durability of the 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) pretreated resin-to-zirconia bonding and conducted a meta-analysis to provide clinical guidance on zirconia bonding strategies. Methods: A comprehensive search was conducted on PubMed, Scopus, Web of Science, CNKI, and Wanfang database to identify relevant studies on the resin-to-zirconia bonding after surface pretreatment with 10-MDP. Strict inclusion and exclusion criteria were applied to select appropriate literature and extract essential information and data. The included studies were categorized based on aging methods (water storage, thermocycling, or both), 10-MDP application methods (within primer, adhesive, resin cement, or both), and additional surface treatments (alumina sandblasting, tribochemical silica coating, acid etching, laser etching, and plasma treatment) and were analyzed by Review Manager 5.4. The evaluation indicator was the bonding strength of zirconia after surface pretreatment with 10-MDP. Results: A total of 72 studies were included in the systematic review, with 68 studies eligible for the meta-analysis. The bonding strength of zirconia decreased significantly after aging [P<0.001; mean difference (MD): 5.58; 95%CI: 5.11-6.05]. No significant differences in bonding strength of zirconia were observed after aging when employing various application methods of 10-MDP (all P>0.05). The bonding strength of zirconia was significantly enhanced after aging when 10-MDP was applied in conjunction with additional surface treatments, as compared to the application of 10-MDP alone (P<0.001; MD: 10.17; 95%CI: 8.20-12.14). Conclusions: The bonding strength of zirconia pretreated with 10-MDP exhibited a reduction after undergoing water storage or thermocycling. The application of 10-MDP with additional surface treatments enhanced the bonding strength of zirconia after aging, while the application methods of 10-MDP did not exert an influence.目的： 通过系统评价和荟萃分析探讨10-甲基丙烯酰氧癸二氢磷酸酯（10-MDP）媒介的氧化锆-树脂粘接耐久性，为氧化锆粘接策略的选择提供参考。 方法： 对Pubmed、Scopus、Web of Science、中国知网和万方数据库进行检索，查找10-MDP媒介的氧化锆-树脂粘接相关文献。根据纳入标准和排除标准筛选文献，提取所需数据。根据不同的老化方式（水储存老化、冷热循环老化、冷热循环+水储存老化）、10-MDP不同应用方法［用于底涂剂和（或）粘接剂和（或）树脂水门汀］以及10-MDP结合其他表面处理（氧化铝喷砂、摩擦化学硅涂层、酸蚀、激光蚀刻、等离子体处理），对纳入的文献进行分类，并用Review Manager 5.4软件进行荟萃分析。评价指标为氧化锆-树脂的粘接强度。 结果： 系统评价共纳入72篇文献，其中68篇文献纳入荟萃分析。老化可显著降低氧化锆-树脂的粘接强度［P<0.001；均数差（MD）：5.58；95%CI：5.11~6.05］，10-MDP不同应用方法未对氧化锆-树脂老化后粘接强度产生显著影响（P>0.05），10-MDP结合其他表面处理时氧化锆-树脂老化后粘接强度显著优于10-MDP单独处理（P<0.001；MD：10.17；95%CI：8.20~12.14）。 结论： 10-MDP媒介的氧化锆-树脂粘接强度在水储存或冷热循环老化后显著下降，应用10-MDP的基础上结合其他表面处理可显著提高氧化锆-树脂老化后粘接强度，而10-MDP不同应用方法不影响氧化锆-树脂的粘接耐久性。.