心肌保护
医学
纤维化
心功能曲线
心脏纤维化
再灌注损伤
心肌梗塞
体内
缺血
下调和上调
心肌纤维化
药理学
内科学
心力衰竭
生物
生物技术
生物化学
基因
作者
Jiawan Wang,Heng Du,Wanrun Xie,Jinmiao Bi,Hao Zhang,Xu Liu,Yuhan Wang,Shaolong Zhang,Anhua Lei,Chuting He,Yuan Hai-long,Jiahe Zhang,Yujing Li,Pengfei Xu,Siqi Liu,Yanan Zhou,Jianghua Shen,Jingdong Wu,Yihong Cai,Chaofan Yang
出处
期刊:Circulation Research
[Ovid Technologies (Wolters Kluwer)]
日期:2024-10-28
卷期号:135 (12): 1161-1174
被引量:53
标识
DOI:10.1161/circresaha.124.325212
摘要
Our proof-of-concept study demonstrates the therapeutic potential of FAP CAR-Ms in alleviating myocardial I/R and potentially opens new avenues for the treatment of a range of heart diseases that include a fibrotic phenotype.
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